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Living Organ Donation

Overview

You may be thinking about donating an organ to a family member or friend. Or you may want to donate an organ to help someone in need. Donating an organ while you're alive is called a "living donation."

Some people who are critically ill need an organ transplant to live. But there are a lot more organs needed than are available. One problem is trying to match a donated organ with the body of the person who gets the organ.

Make sure to think about how giving an organ may affect your emotions. If you're thinking about being an organ donor, you will be asked if you understand how it may affect you and your family. You will also be asked if you understand how it may affect your health. And you will be asked if you feel pressured to donate an organ.

For many people, making a living organ donation can be rewarding. After a successful transplant, most donors feel a special sense of well-being because they may have helped save a life.

What to know

  • Most adults can become organ donors.
  • You can donate to someone you know. Or you can donate to your provincial organ donor organization.
  • Organs you can donate include a kidney or part of the liver, lung, pancreas, or intestines.
  • You need a number of medical tests before you can donate.
  • You don't pay for your medical costs.
  • If you have questions about organ donation, talk to your doctor, a trusted friend, or your faith leader.
  • Most religions allow organ donation.

If you're interested in donating organs or tissues, or if you want to learn more, go to the Canadian Blood Services Organs and Tissues for Life web page (organtissuedonation.ca).

Who can be a living organ donor?

  • You don't have to be in perfect health to donate an organ, as long as the organ you donate is healthy.
  • Adults can sign up to be living organ donors.
  • To be a living donor, you must be:
    • In good general health.
    • Free from diseases that can damage the organs. These include diabetes, uncontrolled high blood pressure, and cancer.
  • If you are or may someday become pregnant, talk with your doctor. Donating an organ could affect your future pregnancies.

Who can you give an organ to?

You can direct your donation to someone you know. It could be a family member, a friend, a co-worker, or a person that you know needs an organ. Or you can donate to someone in need by donating to your provincial organ donation organization. You may also want to talk with your doctor about paired organ exchange. This program helps find organ matches between people who may not know each other. Medical tests will show if your organ is a good match with the recipient.

If you do a directed donation, your organ goes only to the person you name. If you donate to your provincial organ donation organization, your organ will go to an anonymous person. A computer is used to match your organ with possible recipients based on things such as tissue and blood type.

What organs can you donate?

Living donors can donate these organs:

  • A kidney
  • A lobe (part) of a lung
  • A lobe of your liver. (It will grow back to normal size in your body and in the recipient's body over time.)

You can also donate bone marrow, umbilical cord blood, and peripheral blood stem cells.

Becoming a Donor

When you are a possible living donor, your rights and privacy are carefully protected. It's also very important to be informed about the risks of donating an organ. To help you make the best decision for you, you will have a living donor coordinator who will guide you and answer your questions.

Here are the steps for making a donation:

  • Contact Canadian Blood Services.

    You can find more information and the location of the nearest transplant centre.

  • Learn about the risks.

    Risks vary with the organ donated and from person to person.

  • Complete a medical evaluation that includes blood tests.

    The test results can help match you to an organ recipient.

Throughout the planning process, know that it's never too late to change your mind about donating an organ. Talk with your living donor coordinator and others you trust to be sure you're making the right decision for you. Your long-term health is just as important as that of the person who will receive your donation.

Examinations and Tests

Before you become a living organ donor, assessments will be done. These include:

Cross-match for transplant.

This is a blood test that shows whether the recipient's body will reject your donor organ immediately. The cross-match will mix your blood with the recipient's blood to see if proteins in the recipient's blood might attack your donated organ.

Coombs antibody screen.

This test finds out if the recipient has antibodies against a broad range of people. If so, it means there is a higher risk of rejection, even if the cross-match shows a good match.

Blood type.

This is a blood test that shows which type of blood you have—type A, B, O, or AB. Your blood type should be compatible with the organ recipient's blood type. But doctors can sometimes transplant an organ between people with different blood types.

HLA type.

This blood test shows the genetic makeup of your body's cells. We inherit three different kinds of genetic markers from our mothers and three from our fathers. HLA type sometimes plays a role in matching an organ recipient to a donor.

Mental health assessment or social network evaluation.

At these visits, an evaluator looks at your emotional health, your social support, and how donation might affect you. These visits can help give you information to understand your own interests, the future effects on your health, and if you're feeling pressure to donate from another person or from a sense of obligation.

Other screenings may be done, depending on the organ you're donating.

Surgery

Two types of surgery are commonly used to remove an organ or a portion of an organ from a living donor.

  • Open surgery. This involves cutting the skin, muscles, and tissues to remove the organ. When open surgery is done, the person may have more pain and a longer recovery time.
  • Laparoscopic surgery. This is a procedure in which a surgeon makes a number of small incisions and uses scopes to remove the organ from a living donor. Only living donors can have this procedure.

What are the risks?

Living organ donation has risks for both the donor and the person who gets the organ. It's major surgery to take out an organ or a part of an organ. There is always the risk of problems from surgery, such as pain, infection, pneumonia, bleeding, and even death. After the surgery, you may face changes in your body from having one of your organs removed.

Costs

Your costs for the transplant surgery will be paid for by your own provincial health plan or the plan of the person who gets the organ. You may get help with some of your travel expenses. But also think of your costs in terms of lost wages, child care, and possible health problems in the future.

Check with your private insurance provider to find out how your donation may affect your coverage.

Credits

Adaptation Date: 2/8/2023

Adapted By: Alberta Health Services

Adaptation Reviewed By: Alberta Health Services

Adapted with permission from copyrighted materials from Healthwise, Incorporated (Healthwise). This information does not replace the advice of a doctor. Healthwise disclaims any warranty and is not responsible or liable for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.