Early symptoms include headache, fever, pain, and feeling tired. Symptoms change quickly to feeling confused, feeling very nervous or anxious (agitation), and being unable to move (paralysis).
In the advanced stage of illness, people may have severe spasms in their throat, leading to fear of water and swallowing liquids, fear of air and drafts, and then death.
Symptoms can start as early as a few days or as late as several years after contact with the virus. How soon symptoms start depends on where and how serious the wound is.
Deaths from rabies are rare in North America. But worldwide, about 59,000 people die from rabies every year.