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The uric acid urine test measures the amount of uric acid in a sample of urine collected over 24 hours.
Uric acid is made from the natural breakdown of your body's cells. It's also made from the foods you eat. Your kidneys take uric acid out of your blood and put it into urine so that it can leave your body.
But if your body is making too much uric acid, the level in the urine can get too high. And if your kidneys aren't working the way they should, the level of uric acid in the urine can get too low.
High levels of uric acid can cause crystals to form in joints. This causes a painful problem called gout. If gout isn't treated, the crystals can build up and form hard lumpy deposits called tophi.
High uric acid levels can also cause kidney stones.
This test is done to:
No special preparation is needed. You don't need to limit liquids or foods before the test. Make sure you drink enough liquids during the 24-hour test so that you don't get dehydrated.
During the 24-hour period, don't drink alcohol. It lowers the amount of uric acid eliminated by the kidneys.
Many medicines can change the results of this test. Be sure to tell your doctor about all the over-the-counter and prescription medicines you take.
Talk to your doctor about any concerns you have regarding the need for the test, its risks, how it will be done, or what the results may mean. To help you understand the importance of this test, fill out the medical test information form( What is a PDF document? ).
A uric acid urine test is usually done at home. You must collect all the urine you produce in a 24-hour period.
Taking a 24-hour urine sample does not cause pain.
A 24-hour urine sample doesn't cause any problems.
These numbers are just a guide. The range for "normal" varies from lab to lab. Your lab may have a different range. Your lab report should show what range your lab uses for "normal." Also, your doctor will evaluate your results based on your health and other factors. So a number that is outside the normal range here may still be normal for you.
Results are usually available in 1 to 2 days.
250–750 milligrams (mg) per 24-hour urine sample
1.48–4.43 millimoles (mmol) per 24-hour urine sample
Women typically have slightly lower uric acid levels than men.
Many conditions can change uric acid levels. Your doctor will talk with you about any abnormal results that may be related to your symptoms and past health.
Test results might not be accurate if you don't collect exactly 24 hours of urine.
There are many things that can cause your level of uric acid to be too high or too low.
High uric acid levels may be caused by conditions such as:
High levels may also be caused by:
Low uric acid levels may be caused by:
CitationsFischbach FT, Dunning MB III, eds. (2009). Manual of Laboratory and Diagnostic Tests, 8th ed. Philadelphia: Lippincott Williams and Wilkins.Other Works ConsultedChernecky CC, Berger BJ (2008). Laboratory Tests and Diagnostic Procedures, 5th ed. St. Louis: Saunders.Fischbach FT, Dunning MB III, eds. (2009). Manual of Laboratory and Diagnostic Tests, 8th ed. Philadelphia: Lippincott Williams and Wilkins.Pagana KD, Pagana TJ (2010). Mosby's Manual of Diagnostic and Laboratory Tests, 4th ed. St. Louis: Mosby.
Current as ofMarch 28, 2019
Author: Healthwise StaffMedical Review: Anne C. Poinier MD - Internal MedicineAdam Husney MD - Family MedicineMartin J. Gabica MD - Family MedicineNancy Ann Shadick MD, MPH - Internal Medicine, RheumatologyBrian D. O'Brien MD - Internal Medicine
Current as of: March 28, 2019
Author: Healthwise Staff
Medical Review:Anne C. Poinier MD - Internal Medicine & Adam Husney MD - Family Medicine & Martin J. Gabica MD - Family Medicine & Nancy Ann Shadick MD, MPH - Internal Medicine, Rheumatology & Brian D. O'Brien MD - Internal Medicine
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