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Mononucleosis in Children: Care Instructions

The spleen and its location near the stomach

Your Care Instructions

Mononucleosis (mono) is an infection. It's usually caused by the Epstein-Barr virus. People get it through contact with saliva, mucus from the nose and throat, and sometimes tears. A child can get mono if he or she kisses an infected person. Or a child may get it after sharing a glass, fork, or spoon with someone who has mono.

Symptoms include a high fever and a very sore throat. Your child may also have swollen glands and tonsils and feel weak and tired.

Sometimes the virus causes the spleen to swell. The spleen is an organ in the upper left side of the belly. If it ruptures, it's an emergency. So it's important for your child to avoid rough sports or challenging activities while he or she has mono. These can put extra pressure on the spleen.

It takes time to recover from mono. The lymph nodes in your child's neck may be larger than normal for up to 1 month. Most children get better after several weeks. But it could take several months before your child's normal energy is back. Lots of rest will help him or her feel better.

Follow-up care is a key part of your child's treatment and safety. Be sure to make and go to all appointments, and call your doctor or nurse call line if your child is having problems. It's also a good idea to know your child's test results and keep a list of the medicines your child takes.

How can you care for your child at home?

  • Have your child rest and stay in bed as much as possible until he or she feels well enough to be up.
  • Have your child drink plenty of fluids. Choose water and other caffeine-free clear liquids until your child feels better.
  • Be safe with medicines. Have your child take medicines exactly as prescribed. Call your doctor or nurse call line if you think your child is having a problem with his or her medicine.
  • Give your child acetaminophen (Tylenol) or ibuprofen (Advil, Motrin) for fever or pain. Be safe with medicines. Read and follow all instructions on the label.
    • Do not give your child two or more pain medicines at the same time unless the doctor told you to. Many pain medicines have acetaminophen, which is Tylenol. Too much acetaminophen (Tylenol) can be harmful.
    • Do not give aspirin to anyone younger than 18. It has been linked to Reye syndrome, a serious illness.
  • Do not let your child play contact sports or lift anything heavy for 4 weeks. These activities can increase the chance that the spleen may rupture.
  • Try not to spread the virus to others. Make sure your child does not kiss or share dishes, glasses, eating utensils, or toothbrushes. It's hard to know how long your child can spread the virus. This is because he or she could have it long after symptoms go away.

When should you call for help?

Call 911 anytime you think your child may need emergency care. For example, call if:

  • Your child passed out (loses consciousness).

Call your doctor or nurse call line or nurse call line now or seek immediate medical care if:

  • Your child has new or worse belly pain.
  • Your child has signs of needing more fluids. This means your child has sunken eyes and a dry mouth and is passing only a little urine.
  • Your child is dizzy or light-headed or feels like he or she may faint.
  • Your child cannot swallow fluids.

Watch closely for changes in your child's health, and be sure to contact your doctor or nurse call line if:

  • Your child does not get better as expected.

Where can you learn more?

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Care instructions adapted under license by your healthcare professional. If you have questions about a medical condition or this instruction, always ask your healthcare professional. Healthwise, Incorporated disclaims any warranty or liability for your use of this information.