NEW: Express access to COVID-19 vaccine record is now available.

The MyHealth.Alberta.ca Network showcases trusted, easy-to-use health and wellness resources from Alberta Health Services and Alberta-based partner organizations. The network is led by MyHealth.Alberta.ca, Alberta’s source for consumer health information. Our partners are committed to helping Albertans better manage their health and wellbeing. Health experts across Alberta make sure that the information on these sites is accurate and up-to-date. Our partners include

MyHealth.Alberta.ca Network
Health Information and Tools >  Peptic Ulcer Disease

Main Content

Peptic Ulcer Disease

Condition Basics

What are peptic ulcers, and what causes them?

Peptic ulcers in the stomach and duodenum.

Peptic ulcers are sores in the inner lining of the stomach or upper small intestine. They form when the digestive juices produced by the stomach erode or eat away the lining of the digestive tract. Peptic ulcers may form in the lining of the stomach (gastric ulcers) or just below the stomach, at the start of the small intestine (duodenal ulcers).

The most common causes of peptic ulcers are infection with Helicobacter pylori (H. pylori) bacteria and long-term use of non-steroidal anti-inflammatory drugs (NSAIDs). NSAIDs include aspirin, ibuprofen (Advil or Motrin), and naproxen (Aleve).

What are the symptoms?

Symptoms of a peptic ulcer can include a burning, aching, or gnawing pain between the belly button and the breastbone, and belly pain that is temporarily relieved by taking an antacid. Symptoms can also include back pain, loss of appetite, bloating, nausea, and vomiting. Some people have no symptoms.

How are they diagnosed?

Your doctor will ask about your symptoms and do a physical exam. Your doctor may do some simple tests (using your blood, breath, or stool) to look for signs of H. pylori infection. You may have an endoscopy to check the inside of your esophagus, stomach, and small intestine.

How are peptic ulcers treated?

To treat peptic ulcers, most people take medicines that reduce acid in the stomach. If you have an H. pylori infection, you'll also take antibiotics. You can help your ulcer heal by quitting smoking and avoiding alcohol. Using medicines such as aspirin, ibuprofen, or naproxen may increase the chance of your ulcer returning.

Information about Peptic Ulcer Disease

Current as of: October 19, 2023

Author: Ignite Healthwise, LLC Staff

Clinical Review Board
All Healthwise education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.

This information does not replace the advice of a doctor. Ignite Healthwise, LLC, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Information about Peptic Ulcer Disease

Current as of: October 19, 2023

Author: Ignite Healthwise, LLC Staff

Clinical Review Board
All Healthwise education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.