Health Information and Tools >  Depression, Anxiety, and Physical Health Problems
Facebook Tweet Share

Main Content

Depression, Anxiety, and Physical Health Problems

Topic Overview

It's not unusual for mental health problems, especially depression and anxiety, to occur with long-term (chronic) diseases. For example, you may:


People who have chronic diseases such as arthritis, asthma, diabetes, cancer, heart disease, hepatitis C, and stroke often also have depression. Depression also often occurs with chronic pain. Depression may occur with these problems because:

  • The everyday stress of dealing with a chronic disease causes the depression or makes it worse.
  • People who have depression often find it hard to take care of their health, which can lead to health problems.footnote 1
  • People who have depression tend to eat poorly, get less exercise, and smoke.
  • Some chronic diseases change your body chemistry and help cause depression. Cushing's syndrome and an underactive thyroid (hypothyroidism) are examples of this.
  • Depression is linked with some chronic diseases. For example, depression makes coronary artery disease (CAD) and death from heart disease more likely.footnote 1 Also, people with diabetes are more likely to get depression and people with depression are more likely to develop diabetes.footnote 2

If you treat depression, it can improve your health and quality of life.

Here are some things you can do to help yourself.

Here are tools to help a friend or family member who may be depressed:


Anxiety and health problems also are linked. You may feel anxious because you have a health problem. And anxiety can make a health problem worse. For example, older men who have an anxiety disorder are more likely to have a heart attack.footnote 3

To help yourself:

For anxiety and depression, you can:

  • Work closely with all your doctors and tell them about all your health problems. Your family and other medical doctors need to know you are depressed, and any counsellor you talk to needs to know about your physical health problems.
  • Join a support group for depression, anxiety, or the chronic disease you have. You can find support in seminars and groups led by professionals, in groups of others who have the same condition, and in your relationships with family and friends.
  • Eat a balanced diet, and get regular exercise.
  • Avoid alcohol and drugs. They can make depression and anxiety worse.

Many people have concerns about seeking treatment for a mental health problem. You may think it's a sign of weakness, or you don't want people to know about it. It's important to overcome these reasons for not seeking treatment.Treating depression or anxiety is good for your health.



  1. Muskin PR, et al. (2010). Major depressive disorder and other medical illness: A two-way street. Annals of Clinical Psychiatry, 22(4, Suppl 1): S15–S20.
  2. Golden MR, et al. (2003). Updates on syphilis. JAMA, 290(11): 1510–1514.
  3. Shen B-J, et al. (2008). Anxiety characteristics independently and prospectively predict myocardial infarction in men. Journal of the American College of Cardiology, 51(2): 113–119.


Current as of: February 9, 2022

Author: Healthwise Staff
Medical Review:
Kathleen Romito MD - Family Medicine
Donald Sproule MDCM, CCFP - Family Medicine
Lisa S. Weinstock MD - Psychiatry
Christine R. Maldonado PhD - Behavioral Health

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.